اختلاف زمانی زیاد بین دو بارداری موجب افزایش احتمال بروز اتیسم میشود

با توجه به یک مطالعه جدید توسط Kaiser Permanente در مجله Pediatrics منتشر شده است که نشان میدهد کودکان دوم خانواده ها که زودتر از دو سال و یا پس از شش سال پس از ورود خواهر و برادر بزرگتر خود متولد میشوند یک خطر قابل ملاحظه افزایش اختلالات طیف اوتیسم را دارند

Second-born children who are conceived sooner than two years or later than six years after the arrival of their older sibling have a substantially increased risk of autism spectrum disorders, according to a new Kaiser Permanente study published in the journal Pediatrics.

The findings support the World Health Organization’s recommendation of spacing pregnancies a minimum of two years apart.

“Interpregnancy intervals – the time from the first birth to conception of the second child – may be a factor in autism risk,” said Ousseny Zerbo, PhD, research fellow with the Kaiser Permanente Division of Research and the study’s lead author. “And while additional research is needed, our study adds to the growing body of evidence about various risk factors for autism.”

با توجه به یک مطالعه جدید توسط Kaiser Permanente در مجله Pediatrics منتشر شده است که نشان میدهد کودکان دوم خانواده ها که زودتر از دو سال و یا پس از شش سال پس از ورود خواهر و برادر بزرگتر خود متولد میشوند یک خطر قابل ملاحظه افزایش اختلالات طیف اوتیسم را دارند

این یافته توصیه سازمان جهانی بهداشت در خصوص فاصله حاملگی حداقل دو سال از هم را نیز حمایت میکند.

به گفته ی Ousseny Zerbo  محقق این پروژه، فواصل زمانی بین حاملگی از اولین تولد تا فرزند دوم – ممکن است یک عامل در خطر ابتلا به اوتیسم باشد و در حالی که تحقیقات بیشتری مورد نیاز است، مطالعه ما به شواهد در مورد عوامل خطر مختلف برای بروز و ابتلا به اوتیسم می افزاید.

ترجمه:  محمد بهمنی – آسیب شناس گفتار و زبان

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The profit deca has that supersedes regular testosterone,
is that it has much more of a constructive impact on the joints.
Insulin is not a steroid nevertheless it still makes its way into the steroids listing due to
its importance and uses within the anabolic development of muscles.
This peptide hormone is similar to HGH because it helps in the constructing of muscle tissue
from the amino acids coming into the cells.
Insulin instigates biochemical reactions in the muscle that improve protein synthesis.
A lot is alleged about steroids and what they will do for you,
and there may be a lengthy standing debate on whether or not or not they are price it in terms of bodybuilding,
constructing muscle mass and dropping body fat. Over the years
steroids have been offered as a drug that can flip anyone into a superhuman, and so they have become extra prominent amongst younger generations.

Fashionable bodybuilders posing on levels get plenty of
hate due to their bloated guts, and insulin additionally contributes to this.
Synthetic development hormone remedy has been available for some time now, and its primary use is for people who have hormonal points.
Men who develop infertility on account of anabolic steroid use could
also be given drugs to assist restore fertility. Weigh
the benefits and risks of corticosteroids, corresponding to prednisone, when choosing a medication.
Lengthy time period, non-medical uses are linked to heart issues, unwanted physical changes,
and aggression.
However with time, Oxymetholone gained its recognition in sports activities, due to well-known bodybuilders who marketed it
as an inexpensive substitute for Danabol, and the rest is historical past.

Along with its wanted effects, a medicine could trigger
some negative effects. Though not all of
these unwanted facet effects may happen, if they do happen they could need medical attention. It is essential that your doctor verify your progress at common visits to make sure this drugs
is working properly and to decide should you ought to continue to obtain it.
Ask your healthcare skilled how you must dispose of any medication you do not use.
If you miss a dose of this medicine, take it as
soon as potential.
The evaluation of VAS rating results is proven under in Desk 6, with 5/9 research evaluated using VAS.

Qvistgaard even showed CS to be superior to HA and placebo, additionally they
showed HA to lower pain scores additional than placebo [41].
De Rezende reveals CS + 4 ml of HA to be the simplest option at decreasing pain scores when compared to
CS by itself or conjugated with 2/6 ml of HA [50]. CS offered no improvement on ache scores when in comparison with ketorolac in a single examine.

There is growing concern worldwide in regards to the non-medical use of illegal steroids
list (Glenda) and their
results. For athletes, increasing muscle mass can also promote strength, which can enhance strength-based sports activities efficiency.
Anabolic steroids are manufactured medication that intently resemble the hormone
testosterone or other androgens. Corticosteroids, since
they suppress the immune system, can result in a rise in the rate of infections and
scale back the effectiveness of vaccines and antibiotics.

The farthest carbon away from the carboxyl group is numbered because
the omega (ω) carbon, and if the double bond is between the third and fourth carbon from that finish, it is called an omega-3 fatty acid.
Nutritionally necessary as a end result of the physique does not make them,
omega-3 fatty acids embrace alpha-linoleic acid (ALA),
eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA),
all of that are polyunsaturated. Research signifies that
omega-3 fatty acids scale back the risk of sudden dying
from heart assaults, scale back triglycerides in the blood, decrease blood pressure, and
prevent thrombosis by inhibiting blood clotting.
Some persistent forms of lung irritation, such as chronic obstructive pulmonary disease
(COPD) or asthma can be managed with anti-inflammatories.
Inhaled steroids are used extensively for continual lung diseases as a result of they help
with inflammation which can cause long-term harm to the lungs.
In uncommon cases, individuals could have a severe allergic reaction to steroids, often known as anaphylaxis.
It may cause a variety of severe symptoms and, if left untreated, could be life-threatening.

The outlook for steroid use in allergy symptoms is usually
constructive, providing effective aid for many individuals.

It is pretty evident that Oxymetholone could be very highly
effective, however with out following your regular train routine and diet, you
may fail to realize one of the best result. After tapping
into the perks of Oxymetholone, we shall now undergo the process
of using the steroid. Folks assume that it causes fats gain, which isn’t true as Oxymetholone retains water, and the inflation or bloating of the body is due
to extra fluid. Furthermore, should you preserve
a proper calorie diet, you will not achieve any hypodermic fats.
Oxymetholone works wonders on the muscle tissue as a result of it
being extra anabolic.
Inhaled steroids are additionally sometimes used along with
oral steroids. Consideration must be made to coach patients about the risk of AS if they have been treated with GC remedy
inside the final year, but haven’t had testing to rule out AS.
In the occasion of severe sickness or surgical procedure, stress dose steroids ought to be considered to prevent
adrenal crisis. Crucial sickness myopathy can also develop in sufferers requiring large doses
of IV GCs and neuromuscular blocking brokers. It is characterized by severe,
diffuse proximal and distal weak point that develops over a quantity of days.

Therapy is directed towards discontinuation of GC therapy or dose
reductions as soon as possible, as well as aggressive
administration of underlying medical comorbidities.
Lambert used the SF-36 methodology as a secondary methodology and Jurgensmeier utilised HOOS scores [48, 51].
The nine research reported outcomes at 1 week (1), 2 weeks (2), 3 weeks (1),
1 month (5), 2 months (2), 3 months (7), 4 months (1), 6 months (5), 12 months
(2). The summary of the traits of the 9 trials are presented
in Desk 3. The research included 1083 adult patients, 532 received CS,
163 received placebo and 236 obtained HA solely. Mean affected person age was sixty three years and imply BMI was 29 across
5 studies [46, forty nine,50,51,52]. Only 4 studies [41, 49, 52, 50] used Kellgren Lawrence grading techniques to determine radiology severity of the hip OA sufferers, with Kullenberg using the Ahlback technique.


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